Between 1955 and 1961 John Coltrane played in Miles Davis's groups, the years of 'Round About Midnight, Milestones and Kind of Blue. The Best of Miles Davis & John Coltrane is a selection from the Columbia recordings the pair made in that period, with Coltrane as an ever more adventurous foil to Davis's restrained trumpet. The compilation first came out on CD in 2001.

This edition is a 2-LP, the first vinyl release of this compilation, issued for the centenary of both musicians.